内容摘要：Experts say health care providers are more likely to spot potential problems when they listen closely to patients and take what they say seriously.

Experts say health care providers are more likely to spot potential problems when they listen closely to patients and take what they say seriously.

The process starts with modifying genes in pig skin cells in a lab. Revivicor initially deleted a gene that produces a sugar named, which triggers immediate destruction from the human immune system. Next came three-gene “knockouts,” to remove other immune-triggering red flags. Now the company is focusing on 10 gene edits — deleted pig genes and added human ones that together lessen risk of rejection and blood clots plus limit organ size.

They clone pigs with those alterations, similar to how Dolly the sheep was created.Twice a week, slaughterhouses ship Revivicor hundreds of eggs retrieved from sow ovaries. Working in the dark with the light-sensitive eggs, scientists peer through a microscope while suctioning out the maternal DNA. Then they slip in the genetic modifications.A worker at United Therapeutics’ designated pathogen-free facility in Christiansburg, Va., on May 29, 2024 retrives a UV sterilized item from behind a protected barrier within the facility. (AP Photo/Shelby Lum)

A worker at United Therapeutics’ designated pathogen-free facility in Christiansburg, Va., on May 29, 2024 retrives a UV sterilized item from behind a protected barrier within the facility. (AP Photo/Shelby Lum)“Tuck it in nice and smooth,” murmurs senior researcher Lori Sorrells, pushing to just the right spot without rupturing the egg. Mild electric shocks fuse in the new DNA and activate embryo growth.

Ayares, a molecular geneticist who heads Revivicor and helped create the world’s first cloned pigs in 2000, says the technique is “like playing two video games at the same time,” holding the egg in place with one hand and manipulating it with the other. The company’s first modified pig, the

single gene knockout, now is bred instead of cloned. If xenotransplantation eventually works, other pigs with the desired gene combinations would be, too.The FDA’s announcement appears to usurp that advisory panel’s job, Offit said. He added that CDC studies have made clear that booster doses do offer protection against mild to moderate illness for four to six months after the shot even in healthy people.

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.WASHINGTON (AP) — Democrats and Republicans alike raised concerns on Wednesday about deep staffing cuts, funding freezes and far-reaching policy changes overseen by

A bipartisan group of lawmakers questioned Kennedy’s approach to the job, some saying that he has jeopardized vaccine uptake, cancer research and dental health in just a few short months.In combative and at times highly personal rejoinders, Kennedy defended the Trump